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Helping Your Child Cope with CPP

Just talking to your child can make a big difference. It helps if you explain what’s happening to his or her body. Let your child know that puberty is a normal process that everyone goes through in life. It’s just that, for some, puberty happens earlier.

If your child is being teased or bullied by other children, try to get him or her to talk about it with you or with a teacher. It’s also important to remind family members and other adults who know your child to treat your child according to his or her real age, no matter how old your child looks.

Fortunately, today’s medicines can stop the progression of early puberty associated with CPP and save children from the emotional and physical trauma of the condition. The first step toward getting treatment is to find out whether your child actually has CPP. Go to Treating CPP

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Indication

SUPPRELIN® LA (histrelin acetate) implant is used for the treatment of children with central precocious puberty (CPP).

Important Safety Information

SUPPRELIN LA should not be used by women who are or may become pregnant, and in patients who are allergic to gonadotropin releasing hormone (GnRH) or GnRH agonist analogs. Safety and effectiveness in children under 2 years of age has not been determined.

SUPPRELIN LA, like other GnRH agonists, may cause a temporary increase in the blood levels of specific hormones associated with the onset of puberty (estrogen in girls and testosterone in both sexes) during the first week of treatment. This increase may temporarily worsen puberty symptoms during the first week, additionally, you may see new symptoms appear during this period. Within the 4 weeks of treatment with SUPPRELIN LA, hormonal suppression generally occurs and the physical signs of puberty should decrease.

Your doctor should monitor the levels of specific hormones associated with puberty progression, 1 month after starting SUPPRELIN LA and then every 6 months thereafter. Every 6-12 months, height and bone age should be also monitored by your doctor.

During the clinical trial testing of SUPPRELIN LA, the most common side effects involved the implant site and included temporary bruising, pain, soreness, redness of the skin and swelling.

Please talk with your doctor for more information or if you have any questions.

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SUPPRELIN® LA is a registered trademark of Endo Pharmaceuticals.
SP-1007/June 2009

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