Here you can find valuable resources and information about central precocious puberty (CPP) and treatment with SUPPRELIN® LA.
From the first possible signs of early puberty in your young child all the way through diagnosis and treatment, this site contains in-depth information that can be helpful for you.
Please visit our Interactive Family Experience Videos
where you will see and hear other parents talk about their own experiences with CPP.
SUPPRELIN® LA (histrelin acetate) implant is used for the treatment of children with central precocious puberty (CPP).
SUPPRELIN LA should not be used by women who are or may become pregnant, and in patients who are allergic to gonadotropin releasing hormone (GnRH) or GnRH agonist analogs. Safety and effectiveness in children under 2 years of age has not been determined.
SUPPRELIN LA, like other GnRH agonists, may cause a temporary increase in the blood levels of specific hormones associated with the onset of puberty (estrogen in girls and testosterone in both sexes) during the first week of treatment. This increase may temporarily worsen puberty symptoms during the first week, additionally, you may see new symptoms appear during this period. Within the 4 weeks of treatment with SUPPRELIN LA, hormonal suppression generally occurs and the physical signs of puberty should decrease.
Your doctor should monitor the levels of specific hormones associated with puberty progression, 1 month after starting SUPPRELIN LA and then every 6 months thereafter. Every 6-12 months, height and bone age should be also monitored by your doctor.
During the clinical trial testing of SUPPRELIN LA, the most common side effects involved the implant site and included temporary bruising, pain, soreness, redness of the skin and swelling.
Please talk with your doctor for more information or if you have any questions.
